Easy-to-read medicine information about lansoprazole – what it is, how to take lansoprazole safely and possible side effects.
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What is lansoprazole?
Lansoprazole reduces the amount of acid produced in the stomach. It belongs to a group of medicines known as proton pump inhibitors (PPIs). They are used to treat a number of conditions associated with high stomach acid affecting your stomach and gut, such as indigestion, reflux, and ulcers. Lansoprazole can prevent ulcers from forming, or help the healing process where damage has already occurred. It may be given together with antibiotics to get rid of Helicobacter pylori, a bacteria found in the stomach which can cause ulcers. Read more about Helicobacter pylori. Lansoprazole may be used to prevent ulcers caused by medicines such as non-steroidal anti-inflammatory drugs (NSAIDs). Examples of NSAIDs are diclofenac, ibuprofen, naproxen. In New Zealand lansoprazole is available as capsules.
- The usual dose of lansoprazole is 30 mg once a day.
- For some people, 15 mg once a day is enough.
- The pharmacy label on your medicine will tell you how much lansoprazole to take, how often to take it, and any special instructions.
- Your doctor will advise you how long to take lansoprazole for, which can range from a few weeks to months.
How to take lansoprazole
- Take lansoprazole once a day at the same time each day, usually in the morning.
- Swallow the capsule whole with a glass of water. Do not crush or chew - the medicine doesn't work properly if the capsule is crushed or chewed.
- If you have difficulty swallowing the capsule, you can open it and sprinkle the contents on a small amount of soft food or liquid and swallow without chewing. Do not crush the capsule contents.
- Lansoprazole can be taken before or after food, although taking it 30 to 60 minutes before food is preferable.
- If you forget to take your dose, take it as soon as you remember. But, if it is nearly time for your next dose, just take the next dose at the right time. Do not take double the dose.
Avoid long-term use - choose wisely
If you don’t need them, PPIs like lansoprazole should not be taken long term, because of the possible side effects. These include an increased risk of bone fractures, chest infections, kidney problems and nutrient deficiencies such as low magnesium. If you’ve been taking a PPI for reflux for longer than 4 to 8 weeks, and your symptoms seem to be well managed, it’s a good idea to talk to your health care provider about reviewing your medicine. They may recommend stepping down your treatment. This could include:
- reducing your daily dose of lansoprazole
- taking lansoprazole only when you experience the symptoms of heartburn and reflux (also known as on-demand therapy)
- stopping treatment completely as your symptoms may not return.
Read more about PPIs for heartburn and reflux Choosing Wisely, NZ
Precautions - before starting lansoprazole
- Are you pregnant, planning a pregnancy or breast-feeding?
- Do you have problems with your liver?
- Are taking any other medicines? This includes any medicines you are taking which you can buy without a prescription, as well as herbal and complementary medicines.
If so, it’s important that you tell your doctor or pharmacist before you start lansoprazole. Sometimes a medicine isn’t suitable for a person with certain conditions, or it can only be used with extra care.
Possible side effects
Like all medicines lansoprazole can cause side effects, although not everyone gets them. Often side effects improve as your body adjusts to the new medicine.
Rebound acid secretion
When lansoprazole is stopped, a common side effect is rebound acid secretion, where the acid secretion in your stomach increases significantly. This should return to normal within 2 weeks. Because the symptoms of rebound acid secretion are the same as for reflux (such as indigestion, discomfort and pain in your upper stomach and chest, feeling sick and an acid taste in your mouth), it can form an ongoing loop where stopping lansoprazole treatment creates the need to start it again. Rather than restart lansoprazole, you can use medicines that contain both an antacid and an anti-foaming agent, such as Mylanta P oral liquid, Acidex oral liquid or Gaviscon Double Strength tablets, They can be effective for treating rebound acid secretion. You can use these medicines to relieve the symptoms when they occur. Talk to your doctor or pharmacist about how to manage rebound acid secretion.
Other side effects
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Lansoprazole may interact with a few medications and herbal supplements, so check with your doctor or pharmacist before starting lansoprazole or before starting any new medicines.
Medsafe Consumer Information Sheet: Lanzol Relief
New Zealand Formulary Patient Information: lansoprazole
- Proton pump inhibitors: When is enough, enough? BPAC, June 2014
- Proton pump inhibitors and the risk of acute kidney injury. BPAC, July 2016
- Lansoprazole New Zealand Formulary