Ipratropium + salbutamol

Sounds like 'ip-ra-TRO-pee-um' and 'sal-BYOO-ta-mol'

Easy-to-read medicine information about ipratropium + salbutamol – what it is, how to use ipratropium + salbutamol safely and possible side effects.

 Type of medicine  Also called
  • Bronchodilator/reliever
  • Duolin®
  • Combivent®

What is ipratropium + salbutamol?

  • Ipratropium and salbutamol are mixed together in a puffer or inhaler.
  • The combination is used to treat conditions where breathing is a problem, such as chronic obstructive pulmonary disease (COPD), chronic bronchitis, and emphysema.
  • They work by relaxing and opening up the air passages and in that way makes breathing easier, improves shortness of breath, chest tightness and wheezing.
  • Ipratropium and salbutamol belong to a group of medicines known as bronchodilators or relievers (it is called a 'reliever' medicine because it quickly relieves your breathing problems).


  • Follow your doctor's instructions carefully. The pharmacy label on your medicine will tell you how much to use, how often to use it and any special instructions.   
  • Here is some guidance on how to use your inhaler.
  • Here is some guidance on how to use your nebulising solution  

Possible side effects

Side effects What should I do?
  • Headache
  • Dizziness
  • Feeling nervous
  • Fast heart beat
  • Dry mouth
  • A change in voice (hoarse voice)
  • A different taste in your mouth
  • These are common symptoms of ipratropium + salbutamol that will likely go away with time.
  • If the side effects are severe or do not go away contact your health professional. 
  • Get skin rashes, itching, swelling of the face, lips or mouth.
  • Tell your doctor immediately or ring Healthline on 0800 611 116
  • Fast or irregular heart beat that does not go away.
  •  Tell your doctor immediately or ring Healthline on 0800 611 116
  • Difficulty breathing or worsening of your breathing problem.
  •  Tell your doctor immediately or ring Healthline on 0800 611 116

Learn more

New Zealand Formulary Patient Information: Salbutamol and ipratropium

Credits: Sandra Ponen, Pharmacist. Reviewed By: Dr J Bycroft, Health Navigator NZ Last reviewed: 16 Jul 2014