Empagliflozin is used to treat type 2 diabetes. Find out how to take it safely and possible side effects. Empagliflozin is also called Jardiance.
What is empagliflozin?
Empagliflozin is used to treat type 2 diabetes and protect your kidneys and heart. Read more about type 2 diabetes.
Empagliflozin lowers your blood glucose and blood pressure by helping your kidneys get rid of glucose, salt and fluid when you pass urine (pee). Empagliflozin has other benefits such as weight loss, helping your kidneys work better and lowering your chance of having a heart attack or stroke. It may also help you to live longer.
Empagliflozin can be used alone or with other diabetes medicines (such as metformin), along with healthy eating and regular exercise. Empagliflozin is available as a combined tablet with metformin and is called Jardiamet.
- In New Zealand empagliflozin is available as tablets (10 mg and 25 mg).
- The usual starting dose is 1 tablet (10 mg) once a day.
- Depending on your blood glucose levels, your doctor may increase your dose to 25 mg once a day.
- Always take your empagliflozin exactly as your doctor has told you.
- The pharmacy label on your medicine will tell you how much to take, how often to take it and any special instructions.
How to take empagliflozin
- Timing: Take empagliflozin once a day, at the same time each day. Swallow your tablets with a drink of water. You can take empagliflozin with or without food.
- Drink plenty of water: When you start taking empagliflozin, your may pee more but this gets better over a few weeks. Drink enough water so you don't get thirsty. If you've been told by your doctor to limit how much you drink, talk to your healthcare team.
- Avoid or limit alcohol while you are taking empagliflozin: It may affect your blood glucose control and increase your risk of side effects.
- Missed dose: If you forget your dose, take it as soon as you remember that day unless it is less than 12 hours until your next dose. If that's the case, take your next dose at the usual time and skip the forgotten dose.
- Don't run out of tablets: Empagliflozin works best when taken long term. See your healthcare team every 3 months to renew your prescription.
|While you are taking empagliflozin|
Have a sick day plan
If you are unwell irrespective of your symptoms, stop taking empagliflozin. Taking empagliflozin when you are unwell increases your risk of high ketones levels, which can cause a serious but rare side effect called ketoacidosis. Only restart your empagliflozin when you are well AND eating and drinking normally.
Tell your healthcare team straight away of any changes to your diet
If you start eating less or go on a keto (low carbohydrate) diet, this may increase your risk of ketoacidosis.
Keep your genitals clean
Because you will pee more and have more glucose in your urine, you have a higher risk of getting thrush or groin infections.
Prepare before an operation or a procedure
If you are going to have an operation or a procedure such as a colonoscopy, you need to stop your empagliflozin at least 3 days before (2 days before the operation and on the day of the operation or procedure).
Are you pregnant, trying for a baby or breastfeeding?
Tell your doctor if you become pregnant, are trying for a baby or start breastfeeding. You will need to change to another diabetes medicine.
What are the side effects of empagliflozin?
Like all medicines, empagliflozin can cause side effects, although not everyone gets them.
|Common side effects|
These are usually mild and go away with time. Talk to your healthcare team if these side effects cause you problems or don’t go away:
|Did you know that you can report a side effect to a medicine to CARM (Centre for Adverse Reactions Monitoring)? Report a side effect to a product|
|Rare, serious side effects
Tell your healthcare team or Healthline 0800 611 116 immediately if you notice these side effects and tell them you are taking empagliflozin:
Empagliflozin may interact with a few medicines and herbal supplements, so check with your doctor or pharmacist before starting empagliflozin and before starting any new medicines.
Translated medicine leaflets
Download easy-to-understand information for consumers about dabigatran, rivaroxaban and empagliflozin in different languages.
Jardiance Medsafe Consumer Information, NZ
- Empagliflozin NZ Formulary
- Spotlight on empagliflozin Medsafe, NZ, December 2020
- Periprocedural diabetic ketoacidosis (DKA) with SGLT2 inhibitor use NZSSD, January 2020
- SGLT2 inhibitors Type 2 Diabetes Management, NZSSD, 2021
Additional resources for healthcare professionals
Optimising therapy for type 2 diabetes with empagliflozin (Jardiance) Goodfellow MedCases, NZ, 2021