Ankylosing spondylitis (AS) is a form of inflammatory arthritis involving your spine. Pain and stiffness in your back and neck are common symptoms. Men are affected by AS more often than women. AS can be hereditary.
On this page, you can find the following information:
- What is ankylosing spondylitis?
- Who is at risk of getting AS?
- What are the symptoms of AS?
- How is AS diagnosed?
- How is AS treated?
Ankylosing spondylitis (AS) causes ongoing inflammation of soft tissues around the spinal bones (vertebrae). Over time, this inflammation may cause bones in the pelvis and sometimes parts of the spine to fuse together.
This fusing can cause loss of movement of the spine and occasionally can result in a hunched-over posture. In a small number of people, the condition is severe enough for them to stop work or change their employment.
The name Ankylosing spondylitis comes from a combination of Greek words: ankylos meaning fused; spondylos meaning vertebrae; and itis meaning inflammation.
A team of health professionals, including your GP, rheumatologist and physiotherapist, may be involved in your care.
(Arthritis NZ, 2011)
There is a strong tendency for AS to run in families, especially if you have a close relative with AS. About half this risk is related to a single gene called HLA-B27. Other risk factors for AS include the following:
- Crohn’s disease: there is a genetic overlap between AS and inflammation of the bowel.
- Being between the ages of 15 and 35: symptoms usually develop within this age range; it is rare for people older than 40 years to develop it.
- Being male: men are generally more severely affected than women; the reasons for this are unknown.
- Smoking: tends to make AS worse; stopping smoking may be helpful.
The most common symptoms are pain and stiffness in the buttocks, back and neck – often causing people to wake up at night. The stiffness tends to improve once people get moving.
- Pain in the buttocks – can be on one side only.
- Pain in the back or neck – may have a gradual onset but doesn’t go away.
- Stiffness or pain in the morning that improves once you start moving.
- Feeling better after exercise; worse after rest,
- Sleeplessness – especially in the second half of the night.
- Sometimes joints such as knee and tendons, especially around the ankle, can also be inflammed.
- Some people can get inflammation in the eye, causing a red, painful eye.
If these symptoms last for more than three months see your GP to get them checked. If it is ankylosing spondylitis, getting a management plan can help.
Early diagnosis of ankylosing spondylitis is important because impact and potential for loss of mobility can be reduced with correct management. Although there is currently no cure or prevention for AS, the treatment options have widened in recent years so the disease can be well managed.
If you have symptoms of AS, your GP will refer you to a rheumatologist. The diagnosis of AS is made from:
- an assessment of your symptoms
- a physical examination
- blood tests
- x-rays or MRI scans.
Your rheumatologist will explain the result of each test.
Treatment of AS is provided by a team of health professionals such as your GP, rheumatologist, physiotherapist, occupational therapist and orthotist or podiatrist when required. Treatment usually involves medication to reduce inflammation, together with lifestyle measures.
Medicines will decrease inflammation and prevent joint damage. They fall into the following categories.
(non steroidal anti-inflammatory drugs)
(also called steroids)
|Biologic medicines ('biologics')||
Lifestyle measures are also helpful in AS.
Maintaining good posture
Try to maintain an upright posture when standing and sitting. People with AS have a tendency to bend forwards and stoop and this may impact negatively on the spine’s function.
- When standing, keep your body weight balanced and even on both feet with shoulders relaxed, back and down.
- Keep the back of the neck long, allowing the chin to drop slightly forwards.
- Do not stand still for too long and when moving, try to maintain this tall, relaxed posture.
Specially designed chairs and supportive cushions are available to help maintain correct posture while driving or sitting at a desk and simple devices are available to make gardening easier.
Make a habit of being physically active. Performing exercises that are designed to stretch tight muscles and ligaments encourages full mobility and strengthens postural muscles.
- Do exercises designed to increase the strength and endurance of postural muscles, to make it easier to keep in an upright position.
- Specific AS exercises for up to 30 minutes a day, at least 5 times a week (preferably every day), are recommended.
- A moderate, consistent exercise programme is generally the best way to get results for AS.
- Read more about exercise and ankylosing spondylitis.
Plan your activities
Preserve energy by planning or pacing your daily activities. Feeling tired is common for people with AS. Plan and pace your daily activities and vary your tasks so that you allow time to rest and relax.
Practicing relaxation is important especially if your rib joints are involved. Learning how to relax your muscles and getting rid of tension can help to decrease pain, improve sleep and energy levels.
Get a good night’s sleep
Having a good night’s sleep is essential for rest and repair of the body.
- Use a mattress that gives support.
- Sleep in a position that is most comfortable, but if on the side, avoid a lot of bending at the hips and knees.
- A few simple stretching exercises in the evening before going to bed may improve your sleep.
Eat a balanced diet
Although there is no scientific evidence that diet has an effect on AS, a balanced diet helps maintain general health and energy levels. Read more about healthy eating
|Assoc Professor Rebecca Grainger is a senior lecturer in the Department of Medicine and Department of Pathology at the University of Otago, Wellington. She is also a consultant rheumatologist at Hutt Valley DHB. Rebecca is a subject matter expert in osteoarthritis and arthritis.|