Sounds like 'lam-OH-try-jeen'

Easy-to-read medicine information about lamotrigine – what it is, how to take lamotrigine safely and possible side effects.

Type of medicine Also called
  • Anti-epileptic medication (to prevent fits)
  • Lamictal®
  • Arrow-Lamotrigine®
  • Logem®
  • Mogine®

What is lamotrigine?

  • Lamotrigine is used to prevent epilepsy or fits.
  • It is also used to control some mood disorders.
  • Lamotrigine works by calming the nerve activity in the brain, and in this way prevents fits and helps with mood disorders. 


  • The dose of lamotrigine will be different for different people.
  • Your doctor will start you on a low dose, and increase your dose slowly over a few weeks.
  • Always take your lamotrigine exactly as your doctor has told you. The pharmacy label on your medicine will tell you how much lamotrigine to take, how often to take it, and any special instructions.

How to take lamotrigine

  • Swallow your lamotrigine tablets with a glass of water.
  • The dispersible lamotrigine tablets can be popped into some water in a glass, stirred with a spoon and the liquid swallowed when the tablet has disintegrated. They can also be chewed or swallowed whole with a little water.
  • Take lamotrigine at the same times each day (usually once or twice a day).
  • You can take lamotrigine with or without food.
  • Limit or avoid drinking alcohol while you are taking lamotrigine. It can increase your chance of side effects.
  • If you forget to take your dose, take it as soon as you remember that day.
  • But, if it is nearly time for your next dose, just take the next dose at the right time. Do not take double the dose.
  • Keep taking lamotrigine regularly every day. Do not stop taking lamotrigine suddenly; speak to your doctor or nurse before stopping.

Possible side effects

Like all medicines, lamotrigine can cause unwanted side effects, although not everyone gets them. Often unwanted side effects improve as your body gets used to the new medicine.

Side effects What should I do?
  • Feeling sleepy, drowsy or tired
  • Problems with your eye sight such as blurred vision or double vision
  • Be careful when driving or using tools until you know how this medicine affects you.
  • Limit or avoid alcohol.
  • Tell your doctor if troublesome.
  • Headache
  • Back or joint aches and pains

  •  Tell your doctor if troublesome.
  • Feeling sick (nausea)
  • Stomach upset
  • Try taking lamotrigine with food
  • Tell your doctor if troublesome
  • Signs of an allergic reactions such as skin rash, itches, hives
  • Tell your doctor immediately or ring HealthLine


  • Lamotrigine may interact with a few medications and herbal supplements, so check with your doctor or pharmacist.

Learn more

Medsafe Consumer Information Sheet



Credits: Sandra Ponen, Pharmacist..