Sounds like 'is-RAD-i-peen'

Easy-to-read medicine information about isradipine – what is it, how to take isradipine safely and possible side effects

Type of medicineAlso called
  • Belongs to a group of medicines called calcium channel blockers
  • Dynacirc SRO®

What is isradipine?

  • Isradipine is used to treat high blood pressure (hypertension).
  • It works by relaxing your blood vessels so blood can flow more easily, and in this way lowers your blood pressure.


  • The usual dose of isradipine is 2.5 milligrams or 5 milligrams once daily. 
  • Always take your isradipine exactly as your doctor has told you. The pharmacy label on your medicine will tell you how much isradipine to take, how often to take it, and any special instructions.

How to take isradipine

  • Take isradipine once a day. Try to take your doses at the same time each day.
  • Swallow your capsule with a glass of water.
  • You can take isradipine either with or without food.
  • Limit or avoid drinking alcohol while you are taking isradipine. It may increase your chance of side effects such as feeling dizzy.
  • If you forget your dose, take it as soon as you remember that day. But, if it is nearly time for your next dose, just take the next dose at the right time. Do not take double the dose.
  • Do not stop taking isradipine suddenly; speak to your doctor or nurse before stopping.

Possible side effects

Like all medicines, isradipine can cause unwanted side effects, although not everyone gets them. Often unwanted side effects improve as your body gets used to the new medicine.

Side effectsWhat should I do?
  • Tiredness
  • Headache
  • Feeling flushed or hot
  • These are quite common when you first start taking isradipine, and usually go away after the first few days
  • Tell your doctor if troublesome
  • Dizziness
  • Feeling light headed
  • Feeling faint when you stand up
  • Be careful when getting up from either lying down or sitting to avoid falls. These effects puts you at risk of falls and injuries, especially if your are elderly
  • Be careful when driving or using tools until you know how this medicine affects you
  • Swollen ankles or feet
  • Tell your doctor
  • Changes in your heart beat (either too fast or irregular)
  • Tell your doctor
  • Worsening chest pain, shortness of breath, pain in the chest
  • Tell your doctor immediately or ring HealthLine 0800 611 116


  • Check with a pharmacist before taking over the counter medicines such as:
    • Cold or flu tablets containing phenylephrine (e.g. Sudafed PE), or diphenhydramine (e.g. Benadryl Original).
    • Anti-inflammatories such as diclofenac (e.g. Voltaren Rapid), ibuprofen (e.g. Nurofen), mefenamic acid (e.g. Ponstan), naproxen (e.g. Naprogesic).
  • Amlodipine may interact with a few medications and herbal supplements, so check with your doctor or pharmacist.

Learn more

The following links provide further information on isradipine:

Medsafe Consumer Information Sheet:
Dynacirc SRO


Credits: Sandra Ponen, Pharmacist. Reviewed By: Dr J Bycroft, GP