Also called empagliflozin + metformin

Jardiamet is used to treat type 2 diabetes. Find out how to take it safely and possible side effects.

What is Jardiamet?

Jardiamet is used to treat type 2 diabetes and protect your kidneys and heart. It is a combination of 2 medicines, empagliflozin and metformin, in a single tablet. Read more about type 2 diabetes

Jardiamet lowers your blood glucose and blood pressure by helping your kidneys get rid of glucose, salt and fluid when you pass urine (pee). Jardiamet has other benefits such as weight loss, helping your kidneys work better and lowering your chance of having a heart attack or stroke. It may also help you to live longer. Jardiamet is best used together with healthy eating and regular exercise. 

Note: Empagliflozin on its own is called Jardiance. Read more about empagliflozin.


In New Zealand Jardiamet tablets are available in 4 strengths
  • Jardiamet 5 mg/500 mg

  • Jardiamet 12.5 mg/500 mg
  • Jardiamet 5 mg/1,000 mg

  • Jardiamet 12.5 mg/1,000 mg

Check with your doctor or pharmacist which strength you are taking.

  • The usual dose of Jardiamet is 1 tablet 2 times a day.
  • Always take Jardiamet exactly as your doctor has told you. 
  • The pharmacy label on your medicine will tell you how much to take, how often to take it and any special instructions.

How to take Jardiamet

  • Timing: Take Jardiamet 2 times a day, in the morning and the evening. Jardiamet is best taken with or just after food, or a meal, to lessen the chance of stomach upset.
  • Drink plenty of water: When you start taking Jardiamet, your may pee more but this gets better over a few weeks. Drink enough water so you don't get thirsty. If you've been told by your  doctor to limit how much you drink, talk to your healthcare team. 
  • Avoid or limit alcohol while you are taking Jardiamet: It may affect your blood glucose control and increase your risk of side effects.
  • Missed dose: If you forget your dose, take it as soon as you remember that day. But if it is nearly time for your next dose, just take the next dose at the usual time. Do not take double the dose.
  • Don't run out of tablets: Jardiamet works best when taken long term. See your healthcare team every 3 months to renew your prescription.
While you are taking Jardiamet

Have a sick day plan

If you are unwell you should stop your Jardiamet until you are well again. Discuss with your healthcare team when to restart your Jardiamet.

If you have nausea (feeling sick), vomiting (being sick) or tummy pain, you need to have a finger prick blood test immediately at either your GP clinic, after hours medical centre or hospital to check your ketone levels.

High ketone levels can cause a serious but rare side effect, known as ketoacidosis.

Tell your healthcare team straight away of any changes to your diet

If you start eating less or go on a keto (low carbohydrate) diet, this may increase you risk of ketoacidosis.

Keep your genitals clean

Because you will pee more and have more glucose in your urine, you have a higher risk of getting thrush or groin infections.

Regular washing helps prevent this. Women should wash their groin and vulval area 2 times a day and men should wash their penis, foreskin and groin area at least once per day.

Prepare before an operation or a procedure

If you are going to have an operation or a procedure such as a colonoscopy, you need to stop your Jardiamet at least 3 days before (2 days before the operation and on the day of the operation or procedure).

You should discuss with your healthcare team when to stop and restart your Jardiamet.

Are you pregnant, trying for a baby or breastfeeding?

Tell your doctor if you become pregnant, are trying for a baby or start breastfeeding. You will need to change to another diabetes medicine.

What are the side effects of empagliflozin + metformin?

Like all medicines, Jardiamet can cause side effects, although not everyone gets them. 

Common side effects

These are usually mild and go away with time. Talk to your healthcare team if these side effects cause you problems or don’t go away:

  • peeing more often than usual
  • pain or burning feeling when you pee
  • mild skin rash or itchy skin.
Did you know that you can report a side effect to a medicine to CARM (Centre for Adverse Reactions Monitoring)? Report a side effect to a product
Rare and serious side effects 

Tell your healthcare team or Healthline 0800 611 116 immediately if you notice these side effects and tell them you are taking Jardiamet:

  • being sick (vomiting)
  • feeling very thirsty (dehydrated)
  • being confused or unusually tired
  • stomach pain
  • sweet-smelling breath
  • deep or fast breathing
  • fever (high temperature)
  • severe swelling, pain or redness in your anus (bottom) and genitals (vagina and penis)
  • feeling weak, faint, dizzy
  • feeling irritable
  • headache
  • tremor (shakes)
  • blurred vision.


Jardiamet may interact with a few medicines and herbal supplements, so check with your doctor or pharmacist before starting Jardiamet and before starting any new medicines. 

Learn more

Jardiamet Medsafe Consumer Information, NZ


Credits: Sandra Ponen, Pharmacist. Reviewed By: Angela Lambie, Pharmacist, Auckland Last reviewed: 03 Feb 2021