Dabigatran is an anticoagulant, which means it makes it less likely your blood will clot. Find out how to take it safely and possible side effects. Dabigatran is also called Pradaxa.
|Type of medicine||Also called|
What is dabigatran?
Dabigatran is an anticoagulant or blood thinner. It slows down your body’s ability to clot blood. Dabigatran is used to prevent and treat blood clots. Preventing blood clots helps lower your risk of stroke, deep vein thrombosis (DVT) and pulmonary embolism (PE). You may be prescribed dabigatran:
- to prevent stroke if you have atrial fibrillation (irregular heart beat) — atrial fibrillation increases your risk of stroke
- to treat deep vein thrombosis (DVT), which is from blood clots that form in your blood vessels, usually in the legs or arm. Read more about DVT
- to treat pulmonary embolism – which is from blood clots that form in the lungs. Read more about PE
- to prevent DVTs from forming again
- after hip or knee surgery when your risk of blood clots causing DVT or PE is increased.
The following video is about the use of dabigatran in atrial fibrillation.
Video: Bay of Plenty DHB
- Dabigatran capsules are available in different strengths: 75 mg, 110 mg and 150 mg.
- Your doctor or pharmacist will tell you the strength that is right for you. Your dose of dabigatran will depend on what it is being used for.
|Dose of dabigatran|
|To prevent stroke in people with atrial fibrillation||150 mg two times a day|
|To prevent clots after knee or hip surgery||220 mg once daily|
|To treat blood clots||150 mg two times a day|
Always take your dabigatran exactly as your doctor has told you. The pharmacy label will tell you how much dabigatran to take, how often to take it and any special instructions.
|My dabigatran dose||Details|
|I am taking dabigatran for:
||Choose the option that applies to you:
□ Atrial fibrillation
□ After hip or knee surgery, to prevent clots
□ Deep vein thrombosis (DVT)
□ Pulmonary embolism (PE)
|My dose is:|
|For how long:|
How to take dabigatran
- Timing: Take your dabigatran dose at the same times each day. You can take dabigatran with or without food.
- Swallow the capsules whole with a large glass of water. It is important to drink enough water so the capsule doesn't get stuck in your throat. Do not crush, chew or open the capsules. This will release all the medication at once and increase the risk of side effects.
- Missed dose: If you forget to take a dose, do not take a double dose – this increases your risk of bleeding.
- Stroke prevention or blood clots: If the next dose is less than 6 hours away, skip the missed dose and carry on as normal. If there are more than six hours until the next dose, take the missed dose as soon as you remember. Do not take two doses at the same time.
- Knee or hip replacement: Skip the missed dose and carry on as normal at the same time the next day. Do not take two doses at the same time.
- Tell your healthcare provider: It is important to let anyone who gives you treatment know that you are taking dabigatran, including your dentist, pharmacist, podiatrist and nurse. You may need to stop using this medicine for several days before having surgery, dental appointments or medical tests.
- Storing your dabigatran capsules: Dabigatran capsules must be kept in the original foil package to protect them from moisture. If you store the capsules in a pill box or medication reminder box, keep them in the foil packaging. Only remove them from the foil packaging when you are ready to take them.
Precautions – before taking dabigatran
- Do you have problems with your kidneys or liver?
- Are you pregnant or breastfeeding?
- Have you ever had a stomach ulcer or bleeding in your brain?
If so, it’s important that you tell your doctor before you start taking dabigatran. Sometimes a medicine isn’t suitable for a person with certain conditions or taking other medicines, or it can only be used with extra care.
Like all medicines, dabigatran can cause side effects, although not everyone gets them. Common side effects include nausea (feeling sick), indigestion, tummy cramps and headache. These may go away with time. Tell your doctor if troublesome.
Dabigatran increases your risk of bleeding. You might bleed or bruise more easily while you are taking dabigatran.
- Be careful when doing things that may cause bruising and bleeding, such as shaving, clipping your fingernails, brushing and flossing your teeth or playing sports.
- Avoid getting new tattoos and piercings.
- Minor bleeding should usually stop on its own.
- If you have a fall or hurt your head or body, get medical attention immediately, even if you feel okay.
|Signs of severe bleeding|
Contact your healthcare provider urgently if you have any of the following signs of bleeding:
Dabigatran should not be taken with some other medications and herbal supplements, so always check with your doctor or pharmacist before starting dabigatran or before starting any new medicines. Also check with a pharmacist before taking:
- over-the-counter anti-inflammatories such as diclofenac (e.g. Voltaren Rapid), ibuprofen (e.g. Nurofen), naproxen (e.g. Naprogesic)
- herbal extracts such as garlic, ginkgo or ginseng.
Taking these together with dabigatran may increase your risk of bleeding and should be avoided.
The following links have more information on dabigatran:
- The safe and effective use of dabigatran and warfarin in primary care BPAC, NZ, 2017
- An update on managing patients with atrial fibrillation BPAC, NZ, 2017
- Dabigatran etexilate New Zealand Formulary