Quetiapine

In Aotearoa New Zealand quetiapine is available as tablets (25 mg, 100 mg, 200 mg, 300 mg).

• The dose of quetiapine is different for different people. 
• Your doctor will start you on a low dose and increase it over a few days. This allows your body to get used to the medicine and reduces side effects
• Always take your quetiapine exactly as your doctor has told you. The pharmacy label on your medicine will tell you how much quetiapine to take, how often to take it, and any special instructions.

• Quetiapine is usually taken twice a day, for mania or schizophrenia, in the morning and evening. Take your quetiapine doses at the same times each day. If you are taking quetiapine for depression associated with bipolar disorder, take it once a day, at bedtime. 
• You can take quetiapine with or without food. Don't take it with large quantities of grapefruit juice as it changes the levels of quetiapine causing side effects. Read more about grapefruit and medicines.
• If you forget to take your dose, take it as soon as you remember that day. But if it is nearly time for your next dose, just take the next dose at the right time. Don't take double the dose.
• Keep taking quetiapine every day. It usually takes a few weeks to start working and it can take several months before you feel the full benefits. Don't stop taking quetiapine suddenly as your symptoms may return if stopped too early. Talk to your doctor or nurse before stopping.

Here are some things to know when you're taking quetiapine. Other things may be important as well, so ask your healthcare provider what you should know about.

• Avoid alcohol while you are taking quetiapine, especially when you first start treatment. Alcohol can increase your risk of side effects such as dizziness and drowsiness.
• Quetiapine can interact with other medicines. Tell your doctor or pharmacist about all medicines you are taking including over the counter medicines, herbal and complementary medicines or recreational drugs.
• Quetiapine may cause changes in your blood glucose level, cholesterol level and heart function. Your doctor will check your physical health – you may need to have your weight and blood pressure (BP) measured regularly. You may also need blood tests to check your kidneys, liver, and cholesterol and glucose levels.
• Quetiapine is best avoided for people with certain medical conditions such as Parkinson’s disease, epilepsy and depression that is not associated with bipolar disorder and diabetes. Contact your doctor if you have or develop any of these conditions while taking it.
• Contact your doctor if you are pregnant or planning a pregnancy or if you are breastfeeding.
• Quetiapine can make your skin more sensitive to sunlight. Protect yourself, even on a bright but cloudy day; use sunscreen and wear a hat. Don't use sunbeds.

Like all medicines, quetiapine can cause side effects, although not everyone gets them. Often side effects improve as your body gets used to the new medicine.